PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (currently unknown members) increase baicalin's hydrolysis.
Gut
baicalin (PubChem CID: 64982)
unknown
11197087
increase hydrolysis
Gut microbiota normally hydrolyze baicalin into its corresponding aglycone baicalein which is readily absorbable and subject to re-conjugation following absorption. Absence of gut microbiota in germfree rats has resulted in lower levels of baicalin in plasma following oral administration.

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