| 105 | |
| Summary | Gut microbes (genus: Lactobacillus) decrease Irinotecan's toxicity. |
| Gut | |
| Irinotecan (PubChem CID: 60838) | |
| Lactobacillus (Tax ID: 1578) | |
| 33298215 | |
| decrease toxicity | |
| Irinotecan is one of the chemotherapy that could be stopped due to its side effect mucositis. Gut microbiota plays a beneficial role in lowering the severity of gut toxicity. High levels of Lactobacillus and Bifidobacterium have a protective effect on the gut as they short-chain fatty acid producers. |
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