107 | |
Summary | Gut microbes (currently unknown members) decrease Amlodipine's activity. |
Gut | |
Amlodipine (PubChem CID: 2162) | |
unknown | |
29391236 | |
decrease activity | |
Amlodipine is an anti-hypertensive drug. Bacterial hepatic enzyme can metabolite this drug to inactive form. Dehydrogenation of the dihydropyridine moiety produces pyridine metabolite (inactive) which is a major drug metabolite. |
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