| 134 | |
| Summary | Gut microbes (species: Bacteroides fragilis) increase warfarin's toxicity. |
| Gut | |
| warfarin (PubChem CID: 54678486) | |
| Bacteroides fragilis (Tax ID: 817) | |
| 32633584 | |
| increase toxicity | |
| Warfarin is an anti-coagulant drug can be used to treat various type of thrombosis and embolism. The action of warfarin is greatly affected by antibiotics. The use of antibiotics, like fluoroquinolone or B-lactam, which could inhibit Bacteroides fragilis with warfarin leads to increase bleeding risk. This observation suggests B. fragilis have a role in warfarin action. |
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