PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.5 (21 Mar 2021): Spring of Hope! (Release History)

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Summary Gut microbes (genus: Bifidobacterium) decrease Olanzapine's toxicity.
Olanzapine (PubChem CID: 135398745)
Bifidobacterium (Tax ID: 1678)
decrease toxicity
Olanzapine is a drug used in psychosis disorder that can cause weight gain. Two groups of patients receiving olanazpne with or without Bifidobacteriumas probiotics were noted for their weight gain. Contaminant administration with probiotic Bifidobacterium helps significantly in controlling the weight gain at the start of the therapy. after 8 weeks from taking the medication, no differences were noted between the two groups.

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