| 157 | |
| Summary | Gut microbes (species: Coprococcus comes) decrease quinapril's hydrolysis. |
| Gut | |
| quinapril (PubChem CID: 54892) | |
| Coprococcus comes (Tax ID: 410072) | |
| 35538603 | |
| decrease hydrolysis | |
| Hydrolysis of the ester group of the prodrug quinapril mediated by esterase enzyme of Coprococcus comes, leading to the premature activation of quinapril and compromising its anti-hypertensive effect. |
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