| 24 | |
| Summary | Gut microbes (currently unknown members) affect urolithin-A's response to substance. |
| Gut | |
| urolithin-A (PubChem CID: 5488186) | |
| unknown | |
| 19616930 | |
| affect response to substance | |
| Studies in rats showed that pomegranate extract (PE) and its main microbiota-derived metabolite urolithin-A (UROA) favorably modulate the gut microbiota. In healthy subjects, UROA could be the most active anti-inflammatory compound derived from pomegranate ingestion; however, in colon inflammation, the effects are likely due to the nonmetabolized ellagitannin-related fraction of PE. |
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