| 25 | |
| Summary | Gut microbes (currently unknown members) are affected by Splenda's N/A. |
| Gut | |
| Splenda (PubChem CID: 71485) | |
| unknown | |
| 18800291 | |
| are affected by N/A | |
| Evidence indicates that administration of Splenda exerted numerous adverse effects, including reduction in beneficial fecal microbiota ...> the numbers of total anaerobes (bifidobacteria, lactobacilli, Bacteroides, clostridia), and total aerobic bacteria were significantly decreased, increased fecal pH, and enhanced expression levels of P-glycoprotien, CYP3A4, and CYP2D1, which are known to limit the bioavailability of orally administered drugs. |
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