PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

Detailed View

32
Summary Gut microbes (currently unknown members) affect iQ's mutagenesis.
Gut
iQ (PubChem CID: 53462)
unknown
16151094
affect mutagenesis
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a mutagenic/carcinogenic compound formed from meat and fish during cooking. Intestinal bacteria (together with liver enzymes) contribute to its biotransformation. Some bacterial strains are able to produce 7-hydroxy-IQ from IQ, which is also direct mutagen. Examples of bacterial strains: Bacteroides thetaiotaomicron, Clostridium clostridiiforme, Clostridium perfringens, and Escherichia coli.

Browse Drug-Microbiome Relationship
Home