| 32 | |
| Summary | Gut microbes (currently unknown members) affect iQ's mutagenesis. |
| Gut | |
| iQ (PubChem CID: 53462) | |
| unknown | |
| 16151094 | |
| affect mutagenesis | |
| 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a mutagenic/carcinogenic compound formed from meat and fish during cooking. Intestinal bacteria (together with liver enzymes) contribute to its biotransformation. Some bacterial strains are able to produce 7-hydroxy-IQ from IQ, which is also direct mutagen. Examples of bacterial strains: Bacteroides thetaiotaomicron, Clostridium clostridiiforme, Clostridium perfringens, and Escherichia coli. |
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