PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.5 (21 Mar 2021): Spring of Hope! (Release History)

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Summary Gut microbes (genus: Enterococcus) are affected by chloroacetic acid's toxicity.
chloroacetic acid (PubChem CID: 300)
Enterococcus (Tax ID: 1350)
are affected by toxicity
Haloacetic acids, are by-products of drinking water disinfection that can be genotoxic and carcinogenic to rodents. Most of the haloacetic acids were toxic to the cecal microbiota, and especially to the enterococci. On the other hand, although enzymes produced by the normal intestinal microbiota may transform some promutagens and procarcinogens to their biologically active forms, there was no significant alteration of the mutagenicity of these compounds by the intestinal microbiota.

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