PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.5 (21 Mar 2021): Spring of Hope! (Release History)

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Summary Gut microbes (currently unknown members) affect Ethanol's oxidation.
Gut
Ethanol (PubChem CID: 702)
unknown
10026319
affect oxidation
Extrahepatic ethanol metabolism takes place via microbial oxidation in the colon by ADH, mediated by aerobic and facultative anaerobic bacteria. Ciprofloxacin treatment decreased the ethanol elimination rate by 9.4%, with a concomitant decrease in intestinal aerobic and facultative anaerobic bacteria, fecal ADH activity, and acetaldehyde production.

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