4 | |
Summary | Gut microbes (currently unknown members) affect acetaminophen's O-sulfonation. |
Gut | |
acetaminophen (PubChem CID: 1983) | |
unknown | |
19667173 | |
affect O-sulfonation | |
Acetaminophen toxicity is associated with elevated levels of p-cresol, which competes with acetaminophen on the o-sulfonation metabolism. p-cresol is produced by some members of the bacterial community; thus, establishing an assessment of microbiome activity was suggested as a guideline prior to the administration of acetamniophen. |
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