| 49 | |
| Summary | Gut microbes (species: Clostridium leptum) increase nitrazepam's reduction. |
| Gut | |
| nitrazepam (PubChem CID: 4506) | |
| Clostridium leptum (Tax ID: 1535) | |
| 9310649 | |
| increase reduction | |
| The gut microbiota is the primary player in reductive metabolism of nitrazepam by nitroreductase enzymes, and this reduction generates teratogenic activity in humans and rats. |
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