PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (currently unknown members) affect digoxin's reduction.
Gut
digoxin (PubChem CID: 2724385)
unknown
7104181
affect reduction
Some patients treated with digoxin may convert the cardiac glycoside to inactive metabolites such as dihydrodigoxin or , dihydrodigoxigenin. These reduced derivatives have markedly decreased cardiac activity.

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