PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (currently unknown members) affect zonisamide's reduction.
Gut
zonisamide (PubChem CID: 5734)
unknown
9231340
affect reduction
Zonisamide is an anticonvulsant drug. It is primarily metabolised to 2-sulfamoyacetylphenol by reduction of the benzisoxazole ring and the studies concluded that intestinal bacteria play a major role in this reductive metabolism .

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