PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

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Summary Gut microbes (species: Clostridium perfringens) affect Metronidazole's reduction.
Metronidazole (PubChem CID: 4173)
Clostridium perfringens (Tax ID: 1502)
affect reduction
N-(2-hydroxyethyl)-oxamic acid and acetamide are metabolites that result from the reduction of metronidazole by the activity of anaerobic bacteria. Those metabolites are also formed after incubation of metronidazole with either C. perfringens or rat caecal contents.

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