PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (species: Bacteroides eggerthii) affect sorivudine's hydrolysis.
Gut
sorivudine (PubChem CID: 5282192)
Bacteroides eggerthii (Tax ID: 28111)
9110360
affect hydrolysis
Bacteroides species, such as Bacteroides eggerthii , which abundantly exist in human intestines, were identified as the major bacteria, which generate sorivudine’s metabolite (E)- 5-(2-bromovinyl)uracil (BVU) from sorivudine by hydrolysis.

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