| 59 | |
| Summary | Gut microbes (species: Bacteroides eggerthii) affect sorivudine's hydrolysis. |
| Gut | |
| sorivudine (PubChem CID: 5282192) | |
| Bacteroides eggerthii (Tax ID: 28111) | |
| 9110360 | |
| affect hydrolysis | |
| Bacteroides species, such as Bacteroides vulgatus, which abundantly exist in the human intestine, were identified as the major bacteria that generate sorivudine’s metabolite (E)-5-(2-bromovinyl)uracil (BVU) from sorivudine by hydroysis. |
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