PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (currently unknown members) increase Metronidazole's metabolic processing.
Gut
Metronidazole (PubChem CID: 4173)
unknown
231450
increase metabolic processing
Comparison between metronidazole metabolites between germ-free rats and conventional rats showed the excretion of the metabolites by conventional rats only. Furthermore, the metabolites have been retrieved upon adding C. perfringens to metronidazole.

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