PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Gut microbes (currently unknown members) affect ranitidine's metabolic processing.
Gut
ranitidine (PubChem CID: 3001055)
unknown
11564550
affect metabolic processing
A marked decline in ranitidine concentration was noted over time, suggesting degradation and metabolism of the drug by colonic bacteria, analysis indicated that metabolism occurred via cleavage of an N-oxide bond .

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