PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.5 (21 Mar 2021): Spring of Hope! (Release History)

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Summary Gut microbes (currently unknown members) affect insulin's metabolic processing.
Gut
insulin (PubChem CID: 16131098)
unknown
9055189
affect metabolic processing
Peptide drugs, such as insulin and calcitonin, are degraded by some proteolytic enzymes in rat caecal contents. The optimal pH for degrading insulin was found to be 6.8.

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