| 67 | |
| Summary | Gut microbes (currently unknown members) increase 2-methoxyestrone's activity. |
| Gut | |
| 2-methoxyestrone (PubChem CID: 440624) | |
| unknown | |
| 6299367 | |
| increase activity | |
| Members of the gut microbiota are believed to convert 2-methoxy esterone to the active steroid form. Upon incubation of 2-methoxy esterone with isolated ceca of rats, two different reactions were found to take place: oxidoreduction at C17 and demethylation at C2 resulting into the active form. |
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