| 70 | |
| Summary | Gut microbes (phylum: Firmicutes) increase cyclophosphamide's activity. |
| Gut | |
| cyclophosphamide (PubChem CID: 2907) | |
| Firmicutes (Tax ID: 1239) | |
| 24264990 | |
| increase activity | |
| Gram-positive bacteria, translocated into secondary lymphoid organs upon treatment with cyclophosphamide, stimulate the generation of T helper 17 (pT(H)17) cells and memory T(H)1 immune responses. These T cells boost the anticancer effect of cyclophosphamide. |
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