PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.3 (21 March 15)

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Summary Urogenital tract microbes (species: Gardnerella vaginalis) increase tenofovir's metabolic processing.
Urogenital tract
tenofovir (PubChem CID: 464205)
Gardnerella vaginalis (Tax ID: 2702)
increase metabolic processing
"Detectible mucosal tenofovir was lower in non-Lactobacillus women, negatively correlating with Gardnerella vaginalis and other anaerobic bacteria." It is concluded that Gardnerella vaginalis and other anaerobes depleted tenofovir by metabolism.

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