79 | |
Summary | Gut microbes (currently unknown members) increase l‑carnitine's toxicity. |
Gut | |
l‑carnitine (PubChem CID: 10917) | |
unknown | |
23563705 | |
increase toxicity | |
The gut microbiota converts dietary choline and L-carnitine to trimethylamine (TMA), which is further metabolized by the flavine monooxygenase system in the liver to produce the toxic metabolite TMA-N-oxide (TMAO). |
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