| 80 | |
| Summary | Gut microbes (currently unknown members) increase L-tryptophan's toxicity. |
| Gut | |
| L-tryptophan (PubChem CID: 6305) | |
| unknown | |
| 25263219 | |
| increase toxicity | |
| Gut bacteria metabolize L-tryptophan into many products, including the antioxidant indole-3-propionic acid, the neurotransmitter tryptamine, and indole. Hydroxylation and sulfation of indole by hepatic enzymes generate the uremic toxin indoxyl sulfate. |
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