PharmacoMicrobiomics: The Drug-Microbiome Portal

How Bugs Modulate Drugs?

Launched on 11/11/11; Current Release 1.5 (21 Mar 2021): Spring of Hope! (Release History)

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Summary Gut microbes (species: Eubacterium coprostanoligenes) increase Cholesterol's excretion.
Cholesterol (PubChem CID: 5997)
Eubacterium coprostanoligenes (Tax ID: 290054)
increase excretion
Cholesterol can be removed from circulation by the action of Eubacterium coprostanoligenes (gut normal flora) by its conversion to coprostanol, which cannot be absorbed and excreted. Inhibition of cholesterol reabsorption is a clinically validated strategy for lowering cholesterol.

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