82 | |
Summary | Gut microbes (genus: Klebsiella) increase Melamine's toxicity. |
Gut | |
Melamine (PubChem CID: 7955) | |
Klebsiella (Tax ID: 570) | |
23408055 | |
increase toxicity | |
The gut microbiota deaminates melamine to generate ammonia and cyanuric acid. Cyanuric acid forms an insoluble complex with melamine in vivo, leading to renal toxicity. Klebsiella species are associated with cyanuric acid production. |
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