| 84 | |
| Summary | Gut microbes (currently unknown members) increase Ellagic acid's activity. |
| Gut | |
| Ellagic acid (PubChem CID: 5281855) | |
| unknown | |
| 25857357 | |
| increase activity | |
| Ellagic acid, a product of dietary polyphenols found in certain fruits, walnuts, and wines, is metabolized by the gut microbiota to release urolithins. Urolithin A is purported to have anti-proliferative effects in human colon cancer cells, mediating cell cycle arrest and co-treatment in vitro with urolithin A potentiates the anticancer effects of 5-FU and its pro-drug intermediate 5’-deoxy-5-fluorouridine. |
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