| 86 | |
| Summary | Gut microbes (currently unknown members) increase benzoisoquinoline's bioavailability. |
| Gut | |
| benzoisoquinoline (PubChem CID: 160447) | |
| unknown | |
| 26174047 | |
| increase bioavailability | |
| Gut microbes metabolize berberine (a plant-derived benzoisoquinoline alkaloid), allowing its intestinal absorption. It was found that nitroreductases of the gut microbiota convert BBR into dihydroberberine (dhBBR), which has an intestinal absorption rate 5-fold that of BBR in animals. |
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