| 89 | |
| Summary | Gut microbes (currently unknown members) increase Lovastatin's activity. |
| Gut | |
| Lovastatin (PubChem CID: 53232) | |
| unknown | |
| 24947972 | |
| increase activity | |
| This study shows that gut microbes increase the conversion of lovastatin to active metabolites. The plasma concentration of the active hydroxyl acid metabolite of lovastatin is significantly lower in antibiotic-treated rats than in controls. |
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